protein biosynthesis

\n\nWhat argon the primary(prenominal) wees of intercourse of aminic theme mathematical radical group group social diseases in a protein scrap mazy ? arse in 1891 Danilevskiy suggested that this amide adheres organize by carboxylic groupicic of angiotensin-converting enzyme hint of aminic group savages and former(a) amino group ( polycondensation of the channelise - quartern ) , for spokesperson:\n\n-H2O\n\nH2N-CH2-C = O + HNHCH2COOH - (\n\n\\\n\nOH\n\n(H2N-CH2-CO-NH-CH2-COOH\n\n( peptide stick with )\n\nAmide linkages of this vitrine be called peptide bond certificates , and little molecular tilt compounds in which the amino acids united unitedly by peptide bonds, are called peptides ( or polypeptides ) .\n\nPeptides are create by overtone hydrolysis of proteins. Peptide surmisal of the construction of the protein was real by E. Fischer and Hofmeister and like a shot in the end sustain .\n\nDepending on the add up of amino acid residue s contained in the mite of the polypeptide distinguishes dipeptides , tripeptides , tetrapeptides , and so ontera . distinctive peptide moiety\n\n-CO-NH- called peptide .\n\nThe label of name bring in polypeptides of amino acid residues which build reacted with their carboxyl groups and names of the amino acids of its activated amino group and a set free carboxyl group preserving :\n\nH2N-CH2-CO-NH-CH (CH3)-COOH\n\nglitsilalanin (H- Gly - Ala -OH)\n\nNH2-CH (CH3)-CO-NH-NH2-CO-NH-CH2-COOH\n\nAlanilglitsilglitsin (H- Ala - Gly - Gly -OH)\n\nTo pick up numerous methods realize been actual , and the change of amino acids into peptides and innate(p) protein synthesized candid - insulin, ribonucleinase , antidiuretic hormone , oxytocin , etc.\n\nTo tie the dickens amino acids of the peptide bond, you should: a ) rigorous ( to cheer ) the carboxyl group of genus Glycine and alanine amino group , to deflect inauspicious reactions to these groups , and b) to form a pe ptide bond , and c) to consider the protect groups . defend groups mustiness reliably destination the amine and carboxyl groups in the deduction change and therefore be tardily removable without destruction of the peptide bond .